| 9/4/2021 | Florida Atlantic | 14 | at | Florida (6-7) | 35 | at SEC | ||
| 9/11/2021 | Georgia Southern (3-9) | 6 | at | Florida Atlantic | 38 | SBC | ||
| 9/18/2021 | Fordham (6-5) | 14 | at | Florida Atlantic | 45 | Pat (1AA) | ||
| 9/25/2021 | Florida Atlantic | 7 | at | Air Force (10-3) | 31 | at MW | ||
| 10/2/2021 | Florida Intl (1-11,0-8) | 21 | at | Florida Atlantic | 58 | |||
| 10/9/2021 | Florida Atlantic | 14 | at | UAB (9-4,6-2) | 31 | |||
| 10/21/2021 | Florida Atlantic | 38 | at | UNC-Charlotte (5-7,3-5) | 9 | |||
| 10/30/2021 | UTEP (7-6,4-4) | 25 | at | Florida Atlantic | 28 | |||
| 11/6/2021 | Marshall (7-6,5-3) | 28 | at | Florida Atlantic | 13 | |||
| 11/13/2021 | Florida Atlantic | 16 | at | Old Dominion (6-7,5-3) | 30 | |||
| 11/20/2021 | Florida Atlantic | 17 | at | Western Kentucky (9-5,7-2) | 52 | |||
| 11/27/2021 | Middle Tenn State (7-6,4-4) | 27 | at | Florida Atlantic | 17 |
| vs Florida Atlantic | vs Other Opponents | Florida Atlantic compared to OOs | |
| Record: | 7-5 | 69-71 | |
| Points Scored: | 25.75 | 29.86 | 4.11 |
| Points Allowed: | 25.42 | 28.26 | -2.84 |
| Margin: | 0.33 | 1.60 | 1.27 |
| Total Points: | 51.17 | 58.12 | -6.95 |