| 9/3/2016 | LSU | 14 | vs | Wisconsin (11-3) | 16 | Green Bay WI | vs B10 | |
| 9/10/2016 | Jacksonville State (10-2) | 13 | at | LSU | 34 | OVC (1AA) | ||
| 9/17/2016 | Mississippi State (6-7,3-5) | 20 | at | LSU | 23 | |||
| 9/24/2016 | LSU | 13 | at | Auburn (8-5,5-3) | 18 | |||
| 10/1/2016 | Missouri (4-8,2-6) | 7 | at | LSU | 42 | |||
| 10/8/2016 | LSU | vs | Florida (9-4,6-3) | Cancelled WX | ||||
| 10/15/2016 | Southern Miss (7-6) | 10 | at | LSU | 45 | CUSA | ||
| 10/22/2016 | Mississippi (5-7,2-6) | 21 | at | LSU | 38 | |||
| 11/5/2016 | Alabama (14-1,9-0) | 10 | at | LSU | 0 | |||
| 11/12/2016 | LSU | 38 | at | Arkansas (7-6,3-5) | 10 | |||
| 11/19/2016 | Florida (9-4,6-3) | 16 | at | LSU | 10 | |||
| 11/24/2016 | LSU | 54 | at | Texas A&M (8-5,4-4) | 39 | |||
| 12/31/2016 | LSU | 29 | vs | Louisville (9-4) | 9 | Citrus Bowl (Orlando FL) | vs ACC |
| vs LSU | vs Other Opponents | LSU compared to OOs | |
| Record: | 4-8 | 102-54 | |
| Points Scored: | 15.75 | 33.20 | 17.45 |
| Points Allowed: | 28.33 | 22.85 | 5.48 |
| Margin: | -12.58 | 10.35 | 22.93 |
| Total Points: | 44.08 | 56.05 | -11.97 |