| 9/5/2015 | Texas (5-7) | 3 | at | Notre Dame | 38 | B12 | ||
| 9/12/2015 | Notre Dame | 34 | at | Virginia (4-8) | 27 | at ACC | ||
| 9/19/2015 | Georgia Tech (3-9) | 22 | at | Notre Dame | 30 | ACC | ||
| 9/26/2015 | Massachusetts (3-9) | 27 | at | Notre Dame | 62 | MAC | ||
| 10/3/2015 | Notre Dame | 22 | at | Clemson (14-1) | 24 | at ACC | ||
| 10/10/2015 | Navy (11-2) | 24 | at | Notre Dame | 41 | AAC | ||
| 10/17/2015 | Southern California (8-6) | 31 | at | Notre Dame | 41 | P12 | ||
| 10/31/2015 | Notre Dame | 24 | at | Temple (10-4) | 20 | at AAC | ||
| 11/7/2015 | Notre Dame | 42 | at | Pittsburgh (8-5) | 30 | at ACC | ||
| 11/14/2015 | Wake Forest (3-9) | 7 | at | Notre Dame | 28 | ACC | ||
| 11/21/2015 | Notre Dame | 19 | vs | Boston College (3-9) | 16 | Boston MA | vs ACC | |
| 11/28/2015 | Notre Dame | 36 | at | Stanford (12-2) | 38 | at P12 | ||
| 1/1/2016 | Notre Dame | 28 | vs | Ohio State (12-1) | 44 | Fiesta Bowl (Glendale AZ) | vs B10 |
| vs Notre Dame | vs Other Opponents | Notre Dame compared to OOs | |
| Record: | 3-10 | 93-62 | |
| Points Scored: | 24.08 | 30.01 | 5.93 |
| Points Allowed: | 34.23 | 23.03 | 11.20 |
| Margin: | -10.15 | 6.98 | 17.13 |
| Total Points: | 58.31 | 53.04 | 5.27 |