| 9/12/2015 | Massachusetts | 14 | at | Colorado (4-9) | 48 | at P12 | ||
| 9/19/2015 | Temple (10-4) | 25 | at | Massachusetts | 23 | AAC | ||
| 9/26/2015 | Massachusetts | 27 | at | Notre Dame (10-3) | 62 | at ND | ||
| 10/3/2015 | Florida Intl (5-7) | 14 | at | Massachusetts | 24 | CUSA | ||
| 10/10/2015 | Massachusetts | 38 | at | Bowling Green (10-4,8-1) | 62 | |||
| 10/17/2015 | Kent State (3-9,2-6) | 15 | at | Massachusetts | 10 | |||
| 10/24/2015 | Toledo (10-2,6-2) | 51 | at | Massachusetts | 35 | |||
| 10/31/2015 | Massachusetts | 10 | at | Ball State (3-9,2-6) | 20 | |||
| 11/7/2015 | Akron (8-5,5-3) | 17 | at | Massachusetts | 13 | |||
| 11/14/2015 | Massachusetts | 28 | at | Eastern Michigan (1-11,0-8) | 17 | |||
| 11/21/2015 | Miami-Ohio (3-9,2-6) | 20 | at | Massachusetts | 13 | |||
| 11/27/2015 | Massachusetts | 31 | at | Buffalo (5-7,3-5) | 26 |
| vs Massachusetts | vs Other Opponents | Massachusetts compared to OOs | |
| Record: | 9-3 | 63-76 | |
| Points Scored: | 31.42 | 26.67 | -4.75 |
| Points Allowed: | 22.17 | 28.34 | -6.17 |
| Margin: | 9.25 | -1.67 | -10.92 |
| Total Points: | 53.59 | 55.01 | -1.42 |