| 9/4/2010 | Butler Bulldogs 29 @ Albion 13 | |
| 9/11/2010 | Wheaton Thunder 17 @ Albion 6 | |
| 9/18/2010 | Greenville Panthers 10 @ Albion 35 | |
| 9/25/2010 | Albion 14 @ Wisconsin-Stevens Point Pointers 59 | |
| 10/2/2010 | Kalamazoo Hornets 30 @ Albion 27 | † |
| 10/9/2010 | Albion 27 @ Alma Scots 17 | † |
| 10/16/2010 | Hope Flying Dutchmen 14 @ Albion 27 | † |
| 10/23/2010 | Albion 42 @ Olivet Comets 24 | † |
| 10/30/2010 | Adrian Bulldogs 21 @ Albion 38 | † |
| 11/13/2010 | Albion 16 @ Trine Thunder 58 | † |