| 9/2/2010 | Manchester @ Trine | |
| 9/4/2010 | Butler @ Albion | |
| 9/4/2010 | Heidelberg @ Alma | |
| 9/4/2010 | Illinois Wesleyan @ Hope | |
| 9/4/2010 | Bluffton @ Kalamazoo | |
| 9/4/2010 | Adrian @ Wisconsin-Whitewater | |
| 9/4/2010 | Olivet @ Wittenberg | |
| 9/11/2010 | Defiance @ Adrian | |
| 9/11/2010 | Wheaton @ Albion | |
| 9/11/2010 | Trine @ Bluffton | |
| 9/11/2010 | Alma @ Illinois Wesleyan | |
| 9/11/2010 | Manchester @ Kalamazoo | |
| 9/11/2010 | Elmhurst @ Olivet | |
| 9/11/2010 | Hope @ Wisconsin Lutheran | |
| 9/18/2010 | Augustana IL @ Adrian | |
| 9/18/2010 | Rockford @ Alma | |
| 9/18/2010 | Albion @ Greenville | |
| 9/18/2010 | Hope @ Millikin | |
| 9/18/2010 | North Central @ Olivet | |
| 9/18/2010 | Kalamazoo @ Rose-Hulman | |
| 9/18/2010 | Trine @ Wisconsin-River Falls | |
| 9/25/2010 | Kalamazoo @ Ill. Benedictine | |
| 9/25/2010 | Lakeland @ Hope | |
| 9/25/2010 | Alma @ Kentucky Wesleyan | |
| 9/25/2010 | Wheaton @ Olivet | |
| 9/25/2010 | Albion @ Wisconsin-Stevens Point | |
| 10/2/2010 | Trine @ Adrian | † |
| 10/2/2010 | Kalamazoo @ Albion | † |
| 10/2/2010 | Alma @ Hope | † |
| 10/9/2010 | Albion @ Alma | † |
| 10/9/2010 | Hope @ Kalamazoo | † |
| 10/9/2010 | Adrian @ Olivet | † |
| 10/9/2010 | LaGrange @ Trine | |
| 10/16/2010 | Hope @ Albion | † |
| 10/16/2010 | Adrian @ DePauw | |
| 10/16/2010 | Olivet @ Kalamazoo | † |
| 10/16/2010 | Alma @ Trine | † |
| 10/23/2010 | Kalamazoo @ Adrian | † |
| 10/23/2010 | Trine @ Hope | † |
| 10/23/2010 | Albion @ Olivet | † |
| 10/30/2010 | Adrian @ Albion | † |
| 10/30/2010 | Kalamazoo @ Alma | † |
| 10/30/2010 | Olivet @ Trine | † |
| 11/6/2010 | Hope @ Adrian | † |
| 11/6/2010 | Trine @ Kalamazoo | † |
| 11/6/2010 | Alma @ Olivet | † |
| 11/13/2010 | Adrian @ Alma | † |
| 11/13/2010 | Olivet @ Hope | † |
| 11/13/2010 | Albion @ Trine | † |