| 9/2/2021 | Bethel TN | 14 | at | Delta State (5-6) | 48 | at GSC | ||
| 9/11/2021 | Bethel TN | 42 | at | St Andrews (1-9,1-8) | 22 | |||
| 9/18/2021 | Bethel TN | 50 | at | Union KY (2-7,2-7) | 15 | |||
| 9/25/2021 | Reinhardt (9-3,9-2) | 33 | at | Bethel TN | 34 | |||
| 10/2/2021 | Bethel TN | 15 | at | Cumberlands KY (6-4,6-4) | 47 | |||
| 10/9/2021 | Georgetown KY (8-2,8-2) | 24 | at | Bethel TN | 25 | |||
| 10/16/2021 | Bethel TN | 44 | at | Pikeville (4-5,4-5) | 13 | |||
| 10/23/2021 | Bethel TN | 43 | at | Cumberland TN (3-7,3-7) | 24 | |||
| 10/30/2021 | Lindsey Wilson (12-1,11-0) | 41 | at | Bethel TN | 30 | |||
| 11/6/2021 | Thomas More (5-5,5-5) | 24 | at | Bethel TN | 14 | |||
| 11/13/2021 | Campbellsville (1-9,1-9) | 21 | at | Bethel TN | 46 |
| vs Bethel TN | vs Other Opponents | Bethel TN compared to OOs | |
| Record: | 4-7 | 52-51 | |
| Points Scored: | 28.36 | 29.12 | 0.76 |
| Points Allowed: | 32.45 | 26.17 | 6.28 |
| Margin: | -4.09 | 2.95 | 7.04 |
| Total Points: | 60.81 | 55.29 | 5.52 |