| 9/4/2021 | Cumberland TN | 6 | at | Keiser (9-3,9-3) | 45 | |||
| 9/11/2021 | St Thomas FL (8-2,7-2) | 34 | at | Cumberland TN | 6 | |||
| 9/25/2021 | Florida Memorial (2-9,2-8) | 7 | at | Cumberland TN | 19 | |||
| 10/2/2021 | Cumberland TN | 7 | at | Lindsey Wilson (12-1,11-0) | 34 | |||
| 10/9/2021 | Cumberlands KY (6-4,6-4) | 10 | at | Cumberland TN | 14 | |||
| 10/16/2021 | Cumberland TN | 54 | at | Campbellsville (1-9,1-9) | 32 | |||
| 10/23/2021 | Bethel TN (7-4,7-3) | 43 | at | Cumberland TN | 24 | |||
| 10/30/2021 | Cumberland TN | 3 | at | Thomas More (5-5,5-5) | 10 | |||
| 11/6/2021 | Pikeville (4-5,4-5) | 14 | at | Cumberland TN | 9 | |||
| 11/13/2021 | Cumberland TN | 10 | at | Georgetown KY (8-2,8-2) | 28 |
| vs Cumberland TN | vs Other Opponents | Cumberland TN compared to OOs | |
| Record: | 7-3 | 55-41 | |
| Points Scored: | 25.70 | 30.68 | 4.98 |
| Points Allowed: | 15.20 | 24.73 | -9.53 |
| Margin: | 10.50 | 5.95 | -4.55 |
| Total Points: | 40.90 | 55.41 | -14.51 |