| 9/11/2021 | Hardin-Simmons (9-1,7-1) | 27 | at | Sul Ross State | 0 | |||
| 9/18/2021 | Sul Ross State | 7 | at | Austin (1-8) | 16 | at SAA | ||
| 9/25/2021 | Texas Lutheran (3-7,2-6) | 10 | at | Sul Ross State | 12 | |||
| 10/2/2021 | Sul Ross State | 30 | at | Howard Payne (7-3,5-3) | 73 | |||
| 10/9/2021 | North American U (2-4) | 44 | at | Sul Ross State | 37 | Exhibition | None (Unk?) | |
| 10/16/2021 | Sul Ross State | 0 | at | Belhaven (7-3,5-3) | 44 | |||
| 10/23/2021 | Mary Hardin-Baylor (15-0,8-0) | 72 | at | Sul Ross State | 14 | |||
| 10/30/2021 | Sul Ross State | 24 | at | McMurry (2-7,1-7) | 11 | |||
| 11/6/2021 | East Texas Baptist (5-5,3-5) | 31 | at | Sul Ross State | 28 | |||
| 11/13/2021 | Sul Ross State | 15 | at | Southwestern Texas (4-6,3-5) | 49 |
| vs Sul Ross State | vs Other Opponents | Sul Ross State compared to OOs | |
| Record: | 8-2 | 47-42 | |
| Points Scored: | 37.70 | 28.84 | -8.86 |
| Points Allowed: | 16.70 | 28.76 | -12.06 |
| Margin: | 21.00 | 0.08 | -20.92 |
| Total Points: | 54.40 | 57.60 | -3.20 |