| 9/2/2010 | Evangel Crusaders 7 @ Lindenwood 68 | † |
| 9/11/2010 | Lindenwood 69 @ Central Methodist Eagles 7 | † |
| 9/18/2010 | Missouri Valley Vikings 27 @ Lindenwood 45 | † |
| 9/25/2010 | Lindenwood 20 @ MidAmerica Nazarene Pioneers 26 | † |
| 10/2/2010 | Avila Eagles 9 @ Lindenwood 53 | † |
| 10/9/2010 | Lindenwood 48 @ Baker Wildcats 14 | † |
| 10/16/2010 | Culver-Stockton Wildcats 19 @ Lindenwood 90 | † |
| 10/30/2010 | Lindenwood 40 @ Benedictine KS Ravens 24 | † |
| 11/6/2010 | Graceland Yellow Jackets 33 @ Lindenwood 77 | † |
| 11/13/2010 | Lindenwood 29 @ William Jewell Cardinals 18 | † |
| 11/20/2010 | St Francis IN Fighting Saints 46 @ Lindenwood 38 |