| 9/4/2010 | MidAmerica Nazarene Pioneers 42 @ Avila 7 | † |
| 9/18/2010 | Avila 17 @ Baker Wildcats 41 | † |
| 9/25/2010 | Culver-Stockton Wildcats 7 @ Avila 21 | † |
| 10/2/2010 | Avila 9 @ Lindenwood Lions 53 | † |
| 10/9/2010 | Benedictine KS Ravens 47 @ Avila 7 | † |
| 10/16/2010 | Avila 27 @ Graceland Yellow Jackets 21 | † |
| 10/23/2010 | William Jewell Cardinals 41 @ Avila 13 | † |
| 10/30/2010 | Avila 37 @ Evangel Crusaders 41 | † |
| 11/6/2010 | Central Methodist Eagles 38 @ Avila 17 | † |
| 11/13/2010 | Avila 7 @ Missouri Valley Vikings 42 | † |