| 9/6/2009 | Grambling 34 vs S Carolina St 31 (Orlando FL) | |
| 9/12/2009 | Northwestern St 17 @ Grambling 38 | |
| 9/19/2009 | Grambling 27 @ Jackson St 17 | † |
| 9/26/2009 | Grambling 6 @ Oklahoma St 56 | |
| 10/3/2009 | Grambling 32 vs Prairie View 35 (Dallas TX) | † |
| 10/10/2009 | Alabama A&M 20 @ Grambling 41 | † |
| 10/17/2009 | Grambling 23 @ Alabama St 12 | † |
| 10/31/2009 | MS Valley St 7 @ Grambling 50 | † |
| 11/7/2009 | Grambling 42 vs Ark Pine Bluff 49 (Little Rock AR) | † |
| 11/12/2009 | Texas Southern 33 @ Grambling 47 | † |
| 11/28/2009 | Southern Univ 13 vs Grambling 31 (New Orleans LA) | † |