| 9/5/2009 | Prairie View 17 @ Texas Southern 7 | † |
| 9/12/2009 | Texas Southern 0 @ UL Monroe 58 | |
| 9/19/2009 | Texas College 6 @ Texas Southern 75 | |
| 9/26/2009 | Texas Southern 18 @ Texas St 52 | |
| 10/10/2009 | Texas Southern 0 @ Rutgers 42 | |
| 10/17/2009 | Texas Southern 19 @ Jackson St 17 | † |
| 10/31/2009 | Alcorn St 21 @ Texas Southern 51 | † |
| 11/7/2009 | Texas Southern 30 @ MS Valley St 7 | † |
| 11/12/2009 | Texas Southern 33 @ Grambling 47 | † |
| 11/28/2009 | Texas Southern 14 vs Ark Pine Bluff 10 (Dallas TX) | † |
| 12/5/2009 | Southern Univ 25 @ Texas Southern 30 | † |