| 9/1/2005 | Eastern Michigan | 26 | @ | Cincinnati | 28 | ||||
| 9/10/2005 | UL Lafayette | 10 | @ | Eastern Michigan | 31 | ||||
| 9/17/2005 | Eastern Michigan | 0 | @ | #20 Michigan | 55 | ||||
| 9/24/2005 | Eastern Michigan | 23 | @ | Central Michigan | 20 | OT | MAC | ||
| 10/1/2005 | Kent St | 20 | @ | Eastern Michigan | 27 | MAC | |||
| 10/8/2005 | Eastern Michigan | 3 | @ | Toledo | 30 | MAC | |||
| 10/15/2005 | Eastern Michigan | 8 | @ | Northern Illinois | 24 | MAC | |||
| 10/22/2005 | Miami-Ohio | 24 | @ | Eastern Michigan | 23 | MAC | |||
| 11/5/2005 | Western Michigan | 44 | @ | Eastern Michigan | 36 | MAC | |||
| 11/12/2005 | Ball State | 26 | @ | Eastern Michigan | 25 | MAC | |||
| 11/19/2005 | Eastern Michigan | 38 | @ | Buffalo | 14 | MAC |