| 9/3/2022 | St Thomas FL | 26 | at | Butler (7-4) | 31 | at Pio | ||
| 9/10/2022 | St Thomas FL | 31 | at | St Xavier (9-3) | 10 | at MSFA | ||
| 9/17/2022 | North American U (1-8) | 0 | at | St Thomas FL | 52 | None (Unk?) | ||
| 9/24/2022 | Southeastern FL (6-4,3-4) | 14 | at | St Thomas FL | 34 | |||
| 10/1/2022 | Fort Lauderdale (0-2) | at | St Thomas FL | 1 | Forfeit | None (Unk?) | ||
| 10/8/2022 | Keiser (10-4,7-0) | 36 | at | St Thomas FL | 31 | |||
| 10/15/2022 | St Thomas FL | 38 | at | Florida Memorial (2-7,1-6) | 7 | |||
| 10/22/2022 | St Thomas FL | 55 | at | Ave Maria (5-3,3-2) | 33 | |||
| 10/29/2022 | Warner U. (0-8,0-6) | 12 | at | St Thomas FL | 30 | |||
| 11/5/2022 | Webber International (4-4,2-3) | 20 | at | St Thomas FL | 59 | |||
| 11/12/2022 | St Thomas FL | 20 | at | Southeastern FL (6-4,3-4) | 13 |
| vs St Thomas FL | vs Other Opponents | St Thomas FL compared to OOs | |
| Record: | 2-8 | 48-41 | |
| Points Scored: | 17.60 | 24.69 | 7.09 |
| Points Allowed: | 37.60 | 28.60 | 9.00 |
| Margin: | -20.00 | -3.91 | 16.09 |
| Total Points: | 55.20 | 53.29 | 1.91 |