| 9/3/2022 | Thiel | 6 | at | Montclair State (2-8) | 27 | at NJAC | ||
| 9/10/2022 | Allegheny (3-7,3-6) | 34 | at | Thiel | 6 | |||
| 9/17/2022 | Thiel | 16 | at | St Vincent (5-5,5-4) | 24 | |||
| 9/24/2022 | Carnegie Mellon (11-1,8-0) | 35 | at | Thiel | 6 | |||
| 10/1/2022 | Thiel | 27 | at | Bethany WV (1-9,0-9) | 26 | |||
| 10/15/2022 | Thiel | 6 | at | Westminster PA (7-3,7-2) | 41 | |||
| 10/22/2022 | Waynesburg (4-6,3-6) | 34 | at | Thiel | 8 | |||
| 10/29/2022 | Washington & Jefferson (9-2,7-2) | 55 | at | Thiel | 0 | |||
| 11/5/2022 | Geneva (3-7,3-6) | 57 | at | Thiel | 20 | |||
| 11/12/2022 | Thiel | 6 | at | Grove City (8-3,6-3) | 66 |
| vs Thiel | vs Other Opponents | Thiel compared to OOs | |
| Record: | 9-1 | 44-50 | |
| Points Scored: | 39.90 | 24.22 | -15.68 |
| Points Allowed: | 10.10 | 24.79 | -14.69 |
| Margin: | 29.80 | -0.57 | -30.37 |
| Total Points: | 50.00 | 49.01 | 0.99 |