| 9/3/2022 | Juniata (0-10) | 6 | at | Grove City | 63 | Cen | ||
| 9/10/2022 | Geneva (3-7,3-6) | 17 | at | Grove City | 55 | |||
| 9/17/2022 | Grove City | 33 | at | Carnegie Mellon (11-1,8-0) | 40 | |||
| 9/24/2022 | St Vincent (5-5,5-4) | 7 | at | Grove City | 42 | |||
| 10/1/2022 | Case Western Reserve (6-4,6-3) | 13 | at | Grove City | 14 | |||
| 10/8/2022 | Grove City | 55 | at | Bethany WV (1-9,0-9) | 7 | |||
| 10/15/2022 | Grove City | 44 | at | Allegheny (3-7,3-6) | 17 | |||
| 10/22/2022 | Westminster PA (7-3,7-2) | 24 | at | Grove City | 17 | |||
| 11/5/2022 | Grove City | 14 | at | Washington & Jefferson (9-2,7-2) | 31 | |||
| 11/12/2022 | Thiel (1-9,1-8) | 6 | at | Grove City | 66 | |||
| 11/19/2022 | Fairleigh Dickinson-Florham (6-5) | 14 | at | Grove City | 31 | MidAC |
| vs Grove City | vs Other Opponents | Grove City compared to OOs | |
| Record: | 3-8 | 49-54 | |
| Points Scored: | 16.55 | 22.89 | 6.34 |
| Points Allowed: | 39.45 | 25.73 | 13.72 |
| Margin: | -22.90 | -2.84 | 20.06 |
| Total Points: | 56.00 | 48.62 | 7.38 |