| 9/10/2022 | Monmouth IL (9-2,8-1) | 48 | at | Grinnell | 0 | |||
| 9/17/2022 | Grinnell | 28 | at | Lawrence (0-10,0-9) | 7 | |||
| 10/1/2022 | Beloit (1-9,1-8) | 20 | at | Grinnell | 28 | |||
| 10/8/2022 | Grinnell | 6 | at | Ripon (9-1,8-1) | 56 | |||
| 10/15/2022 | Grinnell | 7 | at | Knox (5-5,4-5) | 28 | |||
| 10/22/2022 | Grinnell | 0 | at | Lake Forest (9-2,8-1) | 49 | |||
| 10/29/2022 | Grinnell | 0 | at | Chicago (7-3,6-3) | 58 | |||
| 11/5/2022 | Illinois College (5-4,4-4) | at | Grinnell | PPD | ||||
| 11/12/2022 | Grinnell | 6 | at | Cornell IA (3-7,3-6) | 45 |
| vs Grinnell | vs Other Opponents | Grinnell compared to OOs | |
| Record: | 6-2 | 42-41 | |
| Points Scored: | 38.88 | 25.87 | -13.01 |
| Points Allowed: | 9.38 | 26.54 | -17.16 |
| Margin: | 29.50 | -0.67 | -30.17 |
| Total Points: | 48.26 | 52.41 | -4.15 |