| 9/10/2022 | LaGrange | 10 | at | Berry (7-3) | 56 | at SAA | ||
| 9/17/2022 | Ferrum (1-9) | 38 | at | LaGrange | 44 | ODC | ||
| 9/24/2022 | Methodist (5-5,4-3) | 38 | at | LaGrange | 28 | |||
| 9/30/2022 | LaGrange | 22 | at | North Carolina Wesleyan (3-7,3-4) | 37 | |||
| 10/8/2022 | Maryville (5-5,5-2) | 56 | at | LaGrange | 17 | |||
| 10/22/2022 | LaGrange | 10 | at | Brevard (5-5,5-2) | 24 | |||
| 10/28/2022 | LaGrange | 16 | at | Belhaven (8-2,6-2) | 70 | |||
| 11/5/2022 | Southern Virginia (1-9,1-6) | 35 | at | LaGrange | 21 | |||
| 11/12/2022 | LaGrange | 7 | at | Huntingdon AL (9-2,7-0) | 55 |
| vs LaGrange | vs Other Opponents | LaGrange compared to OOs | |
| Record: | 8-1 | 36-46 | |
| Points Scored: | 45.44 | 25.28 | -20.16 |
| Points Allowed: | 19.44 | 26.91 | -7.47 |
| Margin: | 26.00 | -1.63 | -27.63 |
| Total Points: | 64.88 | 52.19 | 12.69 |