| 9/3/2022 | Cornell IA (3-7) | 7 | at | Coe | 56 | MidW | ||
| 9/10/2022 | Coe | 24 | at | Hope (6-4) | 33 | at MIAA | ||
| 9/17/2022 | Coe | 14 | at | Buena Vista (4-6,3-5) | 3 | |||
| 9/24/2022 | Simpson (1-9,1-7) | 10 | at | Coe | 48 | |||
| 10/8/2022 | Coe | 56 | at | Luther (2-8,2-6) | 10 | |||
| 10/15/2022 | Dubuque (6-4,6-2) | 15 | at | Coe | 14 | |||
| 10/22/2022 | Coe | 27 | at | Loras (5-5,5-3) | 17 | |||
| 10/29/2022 | Central IA (7-3,5-3) | 31 | at | Coe | 37 | |||
| 11/5/2022 | Coe | 34 | at | Nebraska Wesleyan (1-9,0-8) | 14 | |||
| 11/12/2022 | Wartburg (13-1,8-0) | 19 | at | Coe | 14 |
| vs Coe | vs Other Opponents | Coe compared to OOs | |
| Record: | 3-7 | 45-49 | |
| Points Scored: | 15.90 | 30.82 | 14.92 |
| Points Allowed: | 32.40 | 31.16 | 1.24 |
| Margin: | -16.50 | -0.34 | 16.16 |
| Total Points: | 48.30 | 61.98 | -13.68 |