| 9/10/2022 | Simpson | 21 | at | Waldorf (7-4) | 54 | at NSAA | ||
| 9/17/2022 | Simpson | 14 | at | Wisconsin-Stevens Point (1-9) | 35 | at WIAC | ||
| 9/24/2022 | Simpson | 10 | at | Coe (7-3,6-2) | 48 | |||
| 10/1/2022 | Luther (2-8,2-6) | 33 | at | Simpson | 23 | |||
| 10/8/2022 | Simpson | 14 | at | Dubuque (6-4,6-2) | 66 | |||
| 10/15/2022 | Loras (5-5,5-3) | 63 | at | Simpson | 21 | |||
| 10/22/2022 | Simpson | 17 | at | Central IA (7-3,5-3) | 49 | |||
| 10/29/2022 | Nebraska Wesleyan (1-9,0-8) | 41 | at | Simpson | 74 | |||
| 11/5/2022 | Simpson | 9 | at | Wartburg (13-1,8-0) | 81 | |||
| 11/12/2022 | Buena Vista (4-6,3-5) | 26 | at | Simpson | 21 |
| vs Simpson | vs Other Opponents | Simpson compared to OOs | |
| Record: | 9-1 | 44-51 | |
| Points Scored: | 49.60 | 26.84 | -22.76 |
| Points Allowed: | 22.40 | 29.94 | -7.54 |
| Margin: | 27.20 | -3.10 | -30.30 |
| Total Points: | 72.00 | 56.78 | 15.22 |