| 9/3/2022 | Stonehill (4-5) | 33 | at | Bloomsburg | 30 | 2OT | NE (1AA) | |
| 9/10/2022 | Clarion (3-8,3-7) | 3 | at | Bloomsburg | 42 | |||
| 9/17/2022 | Bloomsburg | 20 | at | Edinboro (5-6,4-6) | 23 | OT | ||
| 9/24/2022 | Shippensburg (5-6,5-5) | 31 | at | Bloomsburg | 17 | |||
| 10/1/2022 | West Chester (7-4,6-4) | 16 | at | Bloomsburg | 21 | |||
| 10/8/2022 | Bloomsburg | 0 | at | Kutztown (8-3,8-2) | 24 | |||
| 10/15/2022 | Bloomsburg | 17 | at | Lock Haven (1-10,0-10) | 9 | |||
| 10/22/2022 | East Stroudsburg (4-7,4-6) | 27 | at | Bloomsburg | 21 | |||
| 10/29/2022 | Bloomsburg | 10 | at | Shepherd (13-2,11-1) | 55 | |||
| 11/5/2022 | Millersville (5-6,5-5) | 25 | at | Bloomsburg | 17 | |||
| 11/12/2022 | Bloomsburg | 16 | at | Mercyhurst (2-9,1-9) | 13 |
| vs Bloomsburg | vs Other Opponents | Bloomsburg compared to OOs | |
| Record: | 7-4 | 50-62 | |
| Points Scored: | 23.55 | 23.17 | -0.38 |
| Points Allowed: | 19.18 | 26.06 | -6.88 |
| Margin: | 4.37 | -2.89 | -7.26 |
| Total Points: | 42.73 | 49.23 | -6.50 |