| 9/3/2022 | Davidson | 17 | at | Jacksonville State (9-2) | 35 | at ASUN | ||
| 9/10/2022 | Barton (4-7) | 17 | at | Davidson | 37 | SAC (D2) | ||
| 9/17/2022 | St Andrews (1-10) | 6 | at | Davidson | 56 | MSC (NAIA) | ||
| 9/24/2022 | Davidson | 56 | at | Presbyterian (1-10,0-8) | 24 | |||
| 10/1/2022 | Butler (7-4,5-3) | 0 | at | Davidson | 31 | |||
| 10/8/2022 | Davidson | 16 | at | St Thomas (10-1,8-0) | 27 | |||
| 10/15/2022 | Morehead State (2-9,1-7) | 26 | at | Davidson | 28 | |||
| 10/22/2022 | Davidson | 48 | at | Drake (3-8,3-5) | 14 | |||
| 11/5/2022 | Stetson (4-6,2-5) | 48 | at | Davidson | 56 | 2OT | ||
| 11/12/2022 | Davidson | 14 | at | San Diego (5-5,4-3) | 31 | |||
| 11/19/2022 | Dayton (8-3,6-2) | 23 | at | Davidson | 24 | |||
| 11/26/2022 | Davidson | 0 | at | Richmond (9-4) | 41 | FCS Championship - Round 1 | at CAAF |
| vs Davidson | vs Other Opponents | Davidson compared to OOs | |
| Record: | 4-8 | 59-61 | |
| Points Scored: | 24.33 | 25.43 | 1.10 |
| Points Allowed: | 31.92 | 27.21 | 4.71 |
| Margin: | -7.59 | -1.78 | 5.81 |
| Total Points: | 56.25 | 52.64 | 3.61 |