| 9/3/2022 | Concordia MI (5-5) | 14 | at | Stetson | 24 | MSFA (NAIA) | ||
| 9/10/2022 | Louisiana College (7-4) | 14 | at | Stetson | 45 | Soon (NAIA) | ||
| 9/17/2022 | Princeton (8-2) | 39 | at | Stetson | 14 | Ivy | ||
| 9/24/2022 | Morehead State (2-9,1-7) | 26 | at | Stetson | 38 | |||
| 10/1/2022 | Stetson | at | San Diego (5-5,4-3) | CCD | ||||
| 10/8/2022 | Marist (4-7,4-4) | 45 | at | Stetson | 31 | |||
| 10/22/2022 | Stetson | 20 | at | Dayton (8-3,6-2) | 23 | |||
| 10/29/2022 | Drake (3-8,3-5) | 24 | at | Stetson | 17 | |||
| 11/5/2022 | Stetson | 48 | at | Davidson (8-4,6-2) | 56 | 2OT | ||
| 11/12/2022 | Stetson | 0 | at | St Thomas (10-1,8-0) | 23 | |||
| 11/19/2022 | Presbyterian (1-10,0-8) | 21 | at | Stetson | 42 |
| vs Stetson | vs Other Opponents | Stetson compared to OOs | |
| Record: | 6-4 | 55-54 | |
| Points Scored: | 28.50 | 25.60 | -2.90 |
| Points Allowed: | 27.90 | 25.19 | 2.71 |
| Margin: | 0.60 | 0.41 | -0.19 |
| Total Points: | 56.40 | 50.79 | 5.61 |