| 9/3/2021 | Westfield State | 6 | at | Nichols (2-8) | 21 | at CCF | ||
| 9/10/2021 | Western New England (7-4) | 48 | at | Westfield State | 0 | CCF | ||
| 9/17/2021 | Westfield State | 6 | at | Western Connecticut (5-5,4-4) | 42 | |||
| 9/25/2021 | Westfield State | 6 | at | Framingham State (8-3,8-0) | 41 | |||
| 10/2/2021 | Massachusetts Maritime (4-6,3-5) | 16 | at | Westfield State | 8 | |||
| 10/16/2021 | UMass Dartmouth (9-2,6-2) | 26 | at | Westfield State | 16 | |||
| 10/23/2021 | Westfield State | 14 | at | Bridgewater State MA (6-4,6-2) | 47 | |||
| 10/30/2021 | Plymouth State (5-5,5-3) | 17 | at | Westfield State | 7 | |||
| 11/6/2021 | Worcester State (3-7,3-5) | 33 | at | Westfield State | 30 | |||
| 11/13/2021 | Westfield State | 38 | at | Fitchburg State (0-10,0-8) | 20 |
| vs Westfield State | vs Other Opponents | Westfield State compared to OOs | |
| Record: | 9-1 | 40-53 | |
| Points Scored: | 31.10 | 21.80 | -9.30 |
| Points Allowed: | 13.10 | 25.76 | -12.66 |
| Margin: | 18.00 | -3.96 | -21.96 |
| Total Points: | 44.20 | 47.56 | -3.36 |