| 9/4/2021 | William Paterson (4-6) | 21 | at | Western Connecticut | 24 | NJAC | ||
| 9/11/2021 | Albright (2-8) | 33 | at | Western Connecticut | 28 | MidAC | ||
| 9/17/2021 | Westfield State (1-9,1-7) | 6 | at | Western Connecticut | 42 | |||
| 9/24/2021 | Western Connecticut | 17 | at | Bridgewater State MA (6-4,6-2) | 21 | |||
| 10/2/2021 | UMass Dartmouth (9-2,6-2) | 19 | at | Western Connecticut | 34 | |||
| 10/9/2021 | Plymouth State (5-5,5-3) | 16 | at | Western Connecticut | 13 | |||
| 10/16/2021 | Western Connecticut | 21 | at | Framingham State (8-3,8-0) | 35 | |||
| 10/23/2021 | Massachusetts Maritime (4-6,3-5) | 22 | at | Western Connecticut | 20 | |||
| 10/30/2021 | Western Connecticut | 56 | at | Worcester State (3-7,3-5) | 30 | |||
| 11/6/2021 | Western Connecticut | 48 | at | Fitchburg State (0-10,0-8) | 13 |
| vs Western Connecticut | vs Other Opponents | Western Connecticut compared to OOs | |
| Record: | 5-5 | 37-55 | |
| Points Scored: | 21.60 | 20.70 | -0.90 |
| Points Allowed: | 30.30 | 25.59 | 4.71 |
| Margin: | -8.70 | -4.89 | 3.81 |
| Total Points: | 51.90 | 46.29 | 5.61 |