| 9/4/2021 | Monmouth IL | 3 | at | Wartburg (7-3) | 44 | at ARC | ||
| 9/11/2021 | Grinnell (2-8,2-7) | 7 | at | Monmouth IL | 42 | |||
| 9/18/2021 | Monmouth IL | 37 | at | Illinois College (5-5,5-4) | 27 | |||
| 10/2/2021 | Monmouth IL | 42 | at | Lawrence (2-7,1-7) | 0 | |||
| 10/9/2021 | Chicago (8-2,7-2) | 37 | at | Monmouth IL | 40 | |||
| 10/16/2021 | Monmouth IL | 63 | at | Beloit (0-10,0-9) | 3 | |||
| 10/23/2021 | Cornell IA (4-6,4-5) | 14 | at | Monmouth IL | 47 | |||
| 10/30/2021 | Lake Forest (10-1,9-0) | 24 | at | Monmouth IL | 10 | |||
| 11/6/2021 | Monmouth IL | 31 | at | Ripon (6-3,5-3) | 21 | |||
| 11/13/2021 | Knox (3-6,3-6) | 7 | at | Monmouth IL | 38 |
| vs Monmouth IL | vs Other Opponents | Monmouth IL compared to OOs | |
| Record: | 2-8 | 45-43 | |
| Points Scored: | 18.40 | 29.36 | 10.96 |
| Points Allowed: | 35.30 | 28.00 | 7.30 |
| Margin: | -16.90 | 1.36 | 18.26 |
| Total Points: | 53.70 | 57.36 | -3.66 |