| 9/2/2021 | Defiance (1-9) | 7 | at | Capital | 41 | HCA | ||
| 9/18/2021 | Capital | 17 | at | Heidelberg (7-2,6-2) | 48 | |||
| 9/25/2021 | Marietta (4-6,4-5) | 37 | at | Capital | 7 | |||
| 10/2/2021 | Capital | 0 | at | Baldwin-Wallace (8-2,7-2) | 51 | |||
| 10/9/2021 | John Carroll (7-3,7-2) | 38 | at | Capital | 7 | |||
| 10/16/2021 | Capital | 0 | at | Mount Union (13-1,9-0) | 63 | |||
| 10/23/2021 | Capital | 35 | at | Ohio Northern (4-6,3-6) | 28 | |||
| 10/30/2021 | Otterbein (1-9,1-8) | 38 | at | Capital | 33 | |||
| 11/6/2021 | Capital | 21 | at | Wilmington (2-7,2-6) | 24 | |||
| 11/13/2021 | Muskingum (5-5,4-5) | 46 | at | Capital | 27 |
| vs Capital | vs Other Opponents | Capital compared to OOs | |
| Record: | 8-2 | 44-48 | |
| Points Scored: | 38.00 | 26.90 | -11.10 |
| Points Allowed: | 18.80 | 27.36 | -8.56 |
| Margin: | 19.20 | -0.46 | -19.66 |
| Total Points: | 56.80 | 54.26 | 2.54 |