| 9/2/2021 | New Hampshire (3-8,2-6) | 27 | at | Stony Brook | 21 | |||
| 9/11/2021 | Stony Brook | 24 | at | Colgate (5-6) | 3 | at Pat | ||
| 9/18/2021 | Stony Brook | 7 | at | Oregon (10-4) | 48 | at P12 | ||
| 9/25/2021 | Fordham (6-5) | 31 | at | Stony Brook | 14 | Pat | ||
| 10/2/2021 | Stony Brook | 20 | at | Rhode Island (7-4,4-4) | 27 | OT | ||
| 10/9/2021 | Stony Brook | 14 | at | Towson (4-7,3-5) | 21 | |||
| 10/16/2021 | Delaware (5-6,3-5) | 17 | at | Stony Brook | 34 | |||
| 10/23/2021 | Richmond (6-5,4-4) | 14 | at | Stony Brook | 27 | |||
| 11/6/2021 | Stony Brook | 22 | at | Maine (6-5,4-4) | 17 | |||
| 11/13/2021 | Stony Brook | 14 | at | Villanova (10-3,7-1) | 33 | |||
| 11/20/2021 | Albany NY (2-9,1-7) | 14 | at | Stony Brook | 36 |
| vs Stony Brook | vs Other Opponents | Stony Brook compared to OOs | |
| Record: | 6-5 | 58-57 | |
| Points Scored: | 22.91 | 24.29 | 1.38 |
| Points Allowed: | 21.18 | 25.93 | -4.75 |
| Margin: | 1.73 | -1.64 | -3.37 |
| Total Points: | 44.09 | 50.22 | -6.13 |