| 9/2/2021 | Delaware (5-6,3-5) | 34 | at | Maine | 24 | |||
| 9/11/2021 | Maine | 7 | at | James Madison (12-2,7-1) | 55 | |||
| 9/18/2021 | Merrimack (5-6) | 26 | at | Maine | 31 | NE | ||
| 9/25/2021 | Maine | 14 | at | Northern Illinois (9-5) | 41 | at MAC | ||
| 10/9/2021 | Elon (6-5,5-3) | 33 | at | Maine | 23 | |||
| 10/16/2021 | William & Mary (6-5,4-4) | 16 | at | Maine | 27 | |||
| 10/23/2021 | Maine | 19 | at | Albany NY (2-9,1-7) | 16 | |||
| 10/30/2021 | Maine | 45 | at | Rhode Island (7-4,4-4) | 24 | |||
| 11/6/2021 | Stony Brook (5-6,4-4) | 22 | at | Maine | 17 | |||
| 11/13/2021 | Maine | 35 | at | Massachusetts (1-11) | 10 | at Ind | ||
| 11/20/2021 | Maine | 33 | at | New Hampshire (3-8,2-6) | 20 |
| vs Maine | vs Other Opponents | Maine compared to OOs | |
| Record: | 5-6 | 56-61 | |
| Points Scored: | 27.00 | 24.09 | -2.91 |
| Points Allowed: | 25.00 | 27.04 | -2.04 |
| Margin: | 2.00 | -2.95 | -4.95 |
| Total Points: | 52.00 | 51.13 | 0.87 |