| 9/2/2021 | Delaware | 34 | at | Maine (6-5,4-4) | 24 | |||
| 9/11/2021 | St Francis PA (5-6) | 10 | at | Delaware | 27 | NE | ||
| 9/18/2021 | Delaware | 13 | at | Rutgers (5-8) | 45 | at B10 | ||
| 10/2/2021 | Albany NY (2-9,1-7) | 15 | at | Delaware | 20 | |||
| 10/9/2021 | Delaware | 15 | at | Rhode Island (7-4,4-4) | 22 | |||
| 10/16/2021 | Delaware | 17 | at | Stony Brook (5-6,4-4) | 34 | |||
| 10/23/2021 | James Madison (12-2,7-1) | 22 | at | Delaware | 10 | |||
| 10/30/2021 | Dixie State (1-10) | 10 | at | Delaware | 17 | WAC | ||
| 11/6/2021 | William & Mary (6-5,4-4) | 3 | at | Delaware | 24 | |||
| 11/13/2021 | Delaware | 27 | at | Richmond (6-5,4-4) | 51 | |||
| 11/20/2021 | Villanova (10-3,7-1) | 21 | at | Delaware | 13 |
| vs Delaware | vs Other Opponents | Delaware compared to OOs | |
| Record: | 6-5 | 59-58 | |
| Points Scored: | 23.36 | 24.65 | 1.29 |
| Points Allowed: | 19.73 | 23.71 | -3.98 |
| Margin: | 3.63 | 0.94 | -2.69 |
| Total Points: | 43.09 | 48.36 | -5.27 |