| 9/12/2020 | UL Lafayette | 31 | at | Iowa State (9-3) | 14 | at B12 | ||
| 9/19/2020 | UL Lafayette | 34 | at | Georgia State (6-4,4-4) | 31 | |||
| 9/26/2020 | Georgia Southern (8-5,4-4) | 18 | at | UL Lafayette | 20 | |||
| 10/14/2020 | Coastal Carolina (11-1,8-0) | 30 | at | UL Lafayette | 27 | |||
| 10/23/2020 | UL Lafayette | 24 | at | UAB (6-3) | 20 | at CUSA | ||
| 10/31/2020 | UL Lafayette | 44 | at | Texas State (2-10,2-6) | 34 | |||
| 11/7/2020 | Arkansas State (4-7,2-6) | 20 | at | UL Lafayette | 27 | |||
| 11/14/2020 | South Alabama (4-7,3-5) | 10 | at | UL Lafayette | 38 | |||
| 11/21/2020 | Central Arkansas (5-4) | at | UL Lafayette | CCD | SLC (1AA) | |||
| 11/28/2020 | UL Lafayette | 70 | at | UL Monroe (0-10,0-7) | 20 | |||
| 12/4/2020 | UL Lafayette | 24 | at | Appalachian State (9-3,6-2) | 21 | |||
| 12/19/2020 | UL Lafayette | at | Coastal Carolina (11-1,8-0) | CCD SBC Championship | ||||
| 12/26/2020 | UL Lafayette | 31 | vs | Texas-San Antonio (7-5) | 24 | First Responder Bowl | vs CUSA |
| vs UL Lafayette | vs Other Opponents | UL Lafayette compared to OOs | |
| Record: | 1-10 | 80-53 | |
| Points Scored: | 22.00 | 30.83 | 8.83 |
| Points Allowed: | 33.64 | 26.68 | 6.96 |
| Margin: | -11.64 | 4.15 | 15.79 |
| Total Points: | 55.64 | 57.51 | -1.87 |