| 9/3/2020 | South Alabama | 32 | at | Southern Miss (3-7) | 21 | at CUSA | ||
| 9/12/2020 | Tulane (6-6) | 27 | at | South Alabama | 24 | AAC | ||
| 9/24/2020 | UAB (6-3) | 42 | at | South Alabama | 10 | CUSA | ||
| 10/17/2020 | Texas State (2-10,2-6) | 20 | at | South Alabama | 30 | |||
| 10/24/2020 | UL Monroe (0-10,0-7) | 14 | at | South Alabama | 38 | |||
| 10/29/2020 | South Alabama | 17 | at | Georgia Southern (8-5,4-4) | 24 | |||
| 11/7/2020 | South Alabama | 6 | at | Coastal Carolina (11-1,8-0) | 23 | |||
| 11/14/2020 | South Alabama | 10 | at | UL Lafayette (10-1,7-1) | 38 | |||
| 11/21/2020 | Georgia State (6-4,4-4) | 31 | at | South Alabama | 14 | |||
| 11/28/2020 | South Alabama | 38 | at | Arkansas State (4-7,2-6) | 31 | |||
| 12/5/2020 | Troy (5-6,3-4) | 29 | at | South Alabama | 0 |
| vs South Alabama | vs Other Opponents | South Alabama compared to OOs | |
| Record: | 7-4 | 54-56 | |
| Points Scored: | 27.27 | 29.87 | 2.60 |
| Points Allowed: | 19.91 | 29.78 | -9.87 |
| Margin: | 7.36 | 0.09 | -7.27 |
| Total Points: | 47.18 | 59.65 | -12.47 |