| 9/26/2020 | Iowa State (9-3,8-2) | 37 | at | TCU | 34 | |||
| 10/3/2020 | TCU | 33 | at | Texas (7-3,5-3) | 31 | |||
| 10/10/2020 | Kansas State (4-6,4-5) | 21 | at | TCU | 14 | |||
| 10/24/2020 | Oklahoma (9-2,7-2) | 33 | at | TCU | 14 | |||
| 10/31/2020 | TCU | 33 | at | Baylor (2-7,2-7) | 23 | |||
| 11/7/2020 | Texas Tech (4-6,3-6) | 18 | at | TCU | 34 | |||
| 11/14/2020 | TCU | 6 | at | West Virginia (6-4,4-4) | 24 | |||
| 11/28/2020 | TCU | 59 | at | Kansas (0-9,0-8) | 23 | |||
| 12/5/2020 | Oklahoma State (8-3,6-3) | 22 | at | TCU | 29 | |||
| 12/12/2020 | Louisiana Tech (5-5) | 10 | at | TCU | 52 | CUSA | ||
| 12/31/2020 | Arkansas (3-7) | vs | TCU | CCD Texas Bowl | SEC |
| vs TCU | vs Other Opponents | TCU compared to OOs | |
| Record: | 4-6 | 53-49 | |
| Points Scored: | 24.20 | 30.23 | 6.03 |
| Points Allowed: | 30.80 | 29.39 | 1.41 |
| Margin: | -6.60 | 0.84 | 7.44 |
| Total Points: | 55.00 | 59.62 | -4.62 |