| 9/19/2020 | Louisiana Tech | 31 | at | Southern Miss (3-7,2-4) | 30 | |||
| 9/26/2020 | Houston Baptist (1-3) | 38 | at | Louisiana Tech | 66 | SLC (1AA) | ||
| 10/2/2020 | Louisiana Tech | 14 | at | BYU (11-1) | 45 | at Ind | ||
| 10/10/2020 | UTEP (3-5,0-4) | 17 | at | Louisiana Tech | 21 | |||
| 10/17/2020 | Marshall (6-3,3-2) | 35 | at | Louisiana Tech | 17 | |||
| 10/24/2020 | Louisiana Tech | 26 | at | Texas-San Antonio (7-5,5-2) | 27 | |||
| 10/31/2020 | UAB (6-3,4-1) | 34 | at | Louisiana Tech | 37 | 2OT | ||
| 11/7/2020 | Louisiana Tech | at | North Texas (4-6,3-4) | PPD | ||||
| 11/14/2020 | Rice (2-3,2-3) | at | Louisiana Tech | PPD | ||||
| 11/21/2020 | UL Monroe (0-10) | at | Louisiana Tech | CCD Shreveport, LA | SBC | |||
| 11/28/2020 | Louisiana Tech | at | Florida Intl (0-6,0-3) | CCD | ||||
| 12/3/2020 | Louisiana Tech | 42 | at | North Texas (4-6,3-4) | 31 | |||
| 12/12/2020 | Louisiana Tech | 10 | at | TCU (6-4) | 52 | at B12 | ||
| 12/23/2020 | Louisiana Tech | 3 | vs | Georgia Southern (8-5) | 38 | New Orleans Bowl | vs SBC |
| vs Louisiana Tech | vs Other Opponents | Louisiana Tech compared to OOs | |
| Record: | 5-5 | 56-61 | |
| Points Scored: | 34.70 | 28.52 | -6.18 |
| Points Allowed: | 26.70 | 28.68 | -1.98 |
| Margin: | 8.00 | -0.16 | -8.16 |
| Total Points: | 61.40 | 57.20 | 4.20 |