| 9/12/2020 | Eastern Kentucky (3-6) | 10 | at | West Virginia | 56 | OVC (1AA) | ||
| 9/26/2020 | West Virginia | 13 | at | Oklahoma State (8-3,6-3) | 27 | |||
| 10/3/2020 | Baylor (2-7,2-7) | 21 | at | West Virginia | 27 | |||
| 10/17/2020 | Kansas (0-9,0-8) | 17 | at | West Virginia | 38 | |||
| 10/24/2020 | West Virginia | 27 | at | Texas Tech (4-6,3-6) | 34 | |||
| 10/31/2020 | Kansas State (4-6,4-5) | 10 | at | West Virginia | 37 | |||
| 11/7/2020 | West Virginia | 13 | at | Texas (7-3,5-3) | 17 | |||
| 11/14/2020 | TCU (6-4,5-4) | 6 | at | West Virginia | 24 | |||
| 11/28/2020 | Oklahoma (9-2,7-2) | at | West Virginia | PPD | ||||
| 12/5/2020 | West Virginia | 6 | at | Iowa State (9-3,8-2) | 42 | |||
| 12/12/2020 | Oklahoma (9-2,7-2) | at | West Virginia | CCD | ||||
| 12/31/2020 | West Virginia | 24 | vs | Army (9-3) | 21 | Liberty Bowl | vs Ind |
| vs West Virginia | vs Other Opponents | West Virginia compared to OOs | |
| Record: | 4-6 | 66-48 | |
| Points Scored: | 20.50 | 32.02 | 11.52 |
| Points Allowed: | 26.50 | 27.18 | -0.68 |
| Margin: | -6.00 | 4.84 | 10.84 |
| Total Points: | 47.00 | 59.20 | -12.20 |