| 9/12/2020 | Houston Baptist (1-3) | 33 | at | Texas Tech | 35 | SLC (1AA) | ||
| 9/26/2020 | Texas (7-3,5-3) | 63 | at | Texas Tech | 56 | |||
| 10/3/2020 | Texas Tech | 21 | at | Kansas State (4-6,4-5) | 31 | |||
| 10/10/2020 | Texas Tech | 15 | at | Iowa State (9-3,8-2) | 31 | |||
| 10/24/2020 | West Virginia (6-4,4-4) | 27 | at | Texas Tech | 34 | |||
| 10/31/2020 | Oklahoma (9-2,7-2) | 62 | at | Texas Tech | 28 | |||
| 11/7/2020 | Texas Tech | 18 | at | TCU (6-4,5-4) | 34 | |||
| 11/14/2020 | Baylor (2-7,2-7) | 23 | at | Texas Tech | 24 | |||
| 11/28/2020 | Texas Tech | 44 | at | Oklahoma State (8-3,6-3) | 50 | |||
| 12/5/2020 | Kansas (0-9,0-8) | 13 | at | Texas Tech | 16 |
| vs Texas Tech | vs Other Opponents | Texas Tech compared to OOs | |
| Record: | 6-4 | 46-40 | |
| Points Scored: | 36.70 | 30.07 | -6.63 |
| Points Allowed: | 29.10 | 27.70 | 1.40 |
| Margin: | 7.60 | 2.37 | -5.23 |
| Total Points: | 65.80 | 57.77 | 8.03 |