| 9/12/2020 | Syracuse | 6 | at | North Carolina (8-4,7-3) | 31 | |||
| 9/19/2020 | Syracuse | 10 | at | Pittsburgh (6-5,5-5) | 21 | |||
| 9/26/2020 | Georgia Tech (3-7,3-6) | 20 | at | Syracuse | 37 | |||
| 10/10/2020 | Duke (2-9,1-9) | 38 | at | Syracuse | 24 | |||
| 10/17/2020 | Liberty (10-1) | 38 | at | Syracuse | 21 | Ind | ||
| 10/24/2020 | Syracuse | 21 | at | Clemson (10-2,9-1) | 47 | |||
| 10/31/2020 | Wake Forest (4-5,3-4) | 38 | at | Syracuse | 14 | |||
| 11/7/2020 | Boston College (6-5,5-5) | 16 | at | Syracuse | 13 | |||
| 11/20/2020 | Syracuse | 0 | at | Louisville (4-7,3-7) | 30 | |||
| 11/28/2020 | North Carolina State (8-4,7-3) | 36 | at | Syracuse | 29 | |||
| 12/5/2020 | Syracuse | 21 | at | Notre Dame (10-2,9-1) | 45 |
| vs Syracuse | vs Other Opponents | Syracuse compared to OOs | |
| Record: | 10-1 | 61-50 | |
| Points Scored: | 32.73 | 32.72 | -0.01 |
| Points Allowed: | 17.82 | 28.54 | -10.72 |
| Margin: | 14.91 | 4.18 | -10.73 |
| Total Points: | 50.55 | 61.26 | -10.71 |