| 9/5/2020 | Eastern Kentucky (3-6) | 0 | at | Marshall | 59 | OVC (1AA) | ||
| 9/19/2020 | Appalachian State (9-3) | 7 | at | Marshall | 17 | SBC | ||
| 10/10/2020 | Marshall | 38 | at | Western Kentucky (5-7,4-3) | 14 | |||
| 10/17/2020 | Marshall | 35 | at | Louisiana Tech (5-5,4-2) | 17 | |||
| 10/24/2020 | Florida Atlantic (5-4,4-2) | 9 | at | Marshall | 20 | |||
| 10/30/2020 | Marshall | at | Florida Intl (0-6,0-3) | PPD | ||||
| 11/7/2020 | Massachusetts (0-4) | 10 | at | Marshall | 51 | Ind | ||
| 11/14/2020 | Middle Tenn State (3-5,2-3) | at | Marshall | |||||
| 11/21/2020 | UNC-Charlotte (2-4,2-2) | at | Marshall | PPD | ||||
| 12/5/2020 | Rice (2-3,2-3) | 20 | at | Marshall | 0 | |||
| 12/11/2020 | UNC-Charlotte (2-4,2-2) | at | Marshall | CCD | ||||
| 12/18/2020 | UAB (6-3,4-1) | 22 | at | Marshall | 13 | CUSA Championship | ||
| 12/25/2020 | Marshall | 10 | vs | Buffalo (6-1) | 17 | Camelia Bowl | vs MAC |
| vs Marshall | vs Other Opponents | Marshall compared to OOs | |
| Record: | 3-6 | 45-49 | |
| Points Scored: | 12.89 | 26.59 | 13.70 |
| Points Allowed: | 27.00 | 27.16 | -0.16 |
| Margin: | -14.11 | -0.57 | 13.54 |
| Total Points: | 39.89 | 53.75 | -13.86 |