| 10/23/2020 | Iowa | 20 | at | Purdue (2-4,2-4) | 24 | |||
| 10/31/2020 | Northwestern (7-2,6-2) | 21 | at | Iowa | 20 | |||
| 11/7/2020 | Michigan State (2-5,2-5) | 7 | at | Iowa | 49 | |||
| 11/13/2020 | Iowa | 35 | at | Minnesota (3-4,3-4) | 7 | |||
| 11/21/2020 | Iowa | 41 | at | Penn State (4-5,4-5) | 21 | |||
| 11/27/2020 | Nebraska (3-5,3-5) | 20 | at | Iowa | 26 | |||
| 12/5/2020 | Iowa | 35 | at | Illinois (2-6,2-6) | 21 | |||
| 12/12/2020 | Wisconsin (4-3,3-3) | 7 | at | Iowa | 28 | |||
| 12/19/2020 | Michigan (2-4,2-4) | at | Iowa | CCD | ||||
| 12/30/2020 | Iowa | vs | Missouri (5-5) | CCD Music City Bowl | vs SEC |
| vs Iowa | vs Other Opponents | Iowa compared to OOs | |
| Record: | 2-6 | 32-37 | |
| Points Scored: | 16.00 | 26.10 | 10.10 |
| Points Allowed: | 31.75 | 28.12 | 3.63 |
| Margin: | -15.75 | -2.02 | 13.73 |
| Total Points: | 47.75 | 54.22 | -6.47 |