| 10/24/2020 | Penn State | 35 | at | Indiana (6-2,6-1) | 36 | OT | ||
| 10/31/2020 | Ohio State (7-1,6-0) | 38 | at | Penn State | 25 | |||
| 11/7/2020 | Maryland (2-3,2-3) | 35 | at | Penn State | 19 | |||
| 11/14/2020 | Penn State | 23 | at | Nebraska (3-5,3-5) | 30 | |||
| 11/19/2020 | Illinois (2-6,2-6) | 21 | at | Penn State | 56 | |||
| 11/21/2020 | Iowa (6-2,6-2) | 41 | at | Penn State | 21 | |||
| 11/28/2020 | Penn State | 27 | at | Michigan (2-4,2-4) | 17 | |||
| 12/5/2020 | Penn State | 23 | at | Rutgers (3-6,3-6) | 7 | |||
| 12/12/2020 | Michigan State (2-5,2-5) | 24 | at | Penn State | 39 |
| vs Penn State | vs Other Opponents | Penn State compared to OOs | |
| Record: | 5-4 | 28-30 | |
| Points Scored: | 27.67 | 26.97 | -0.70 |
| Points Allowed: | 29.78 | 28.34 | 1.44 |
| Margin: | -2.11 | -1.37 | 0.74 |
| Total Points: | 57.45 | 55.31 | 2.14 |