| 10/23/2020 | Iowa (6-2,6-2) | 20 | at | Purdue | 24 | |||
| 10/31/2020 | Purdue | 31 | at | Illinois (2-6,2-6) | 24 | |||
| 11/7/2020 | Purdue | at | Wisconsin (4-3,3-3) | CCD | ||||
| 11/14/2020 | Northwestern (7-2,6-2) | 27 | at | Purdue | 20 | |||
| 11/20/2020 | Purdue | 31 | at | Minnesota (3-4,3-4) | 34 | |||
| 11/28/2020 | Rutgers (3-6,3-6) | 37 | at | Purdue | 30 | |||
| 12/5/2020 | Nebraska (3-5,3-5) | 37 | at | Purdue | 27 | |||
| 12/12/2020 | Purdue | at | Indiana (6-2,6-1) | CCD |
| vs Purdue | vs Other Opponents | Purdue compared to OOs | |
| Record: | 4-2 | 30-28 | |
| Points Scored: | 29.83 | 25.53 | -4.30 |
| Points Allowed: | 27.17 | 24.24 | 2.93 |
| Margin: | 2.66 | 1.29 | -1.37 |
| Total Points: | 57.00 | 49.77 | 7.23 |