| 10/24/2020 | Penn State (4-5,4-5) | 35 | at | Indiana | 36 | OT | ||
| 10/31/2020 | Indiana | 37 | at | Rutgers (3-6,3-6) | 21 | |||
| 11/7/2020 | Michigan (2-4,2-4) | 21 | at | Indiana | 38 | |||
| 11/14/2020 | Indiana | 24 | at | Michigan State (2-5,2-5) | 0 | |||
| 11/21/2020 | Indiana | 35 | at | Ohio State (7-1,6-0) | 42 | |||
| 11/28/2020 | Maryland (2-3,2-3) | 11 | at | Indiana | 27 | |||
| 12/5/2020 | Indiana | 14 | at | Wisconsin (4-3,3-3) | 6 | |||
| 12/12/2020 | Purdue (2-4,2-4) | at | Indiana | CCD | ||||
| 1/2/2021 | Mississippi (5-5) | 26 | vs | Indiana | 20 | Outback Bowl | SEC |
| vs Indiana | vs Other Opponents | Indiana compared to OOs | |
| Record: | 2-6 | 29-30 | |
| Points Scored: | 20.25 | 30.83 | 10.58 |
| Points Allowed: | 28.88 | 30.68 | -1.80 |
| Margin: | -8.63 | 0.15 | 8.78 |
| Total Points: | 49.13 | 61.51 | -12.38 |