| 9/26/2020 | Florida (8-4,8-3) | 51 | at | Mississippi | 35 | |||
| 10/3/2020 | Mississippi | 42 | at | Kentucky (5-6,4-6) | 41 | |||
| 10/10/2020 | Alabama (13-0,11-0) | 63 | at | Mississippi | 48 | |||
| 10/17/2020 | Mississippi | 21 | at | Arkansas (3-7,3-7) | 33 | |||
| 10/24/2020 | Auburn (6-5,6-4) | 35 | at | Mississippi | 28 | |||
| 10/31/2020 | Mississippi | 54 | at | Vanderbilt (0-9,0-9) | 21 | |||
| 11/14/2020 | South Carolina (2-8,2-8) | 42 | at | Mississippi | 59 | |||
| 11/21/2020 | Mississippi | at | Texas A&M (9-1,8-1) | PPD | ||||
| 11/28/2020 | Mississippi State (4-7,3-7) | 24 | at | Mississippi | 31 | |||
| 12/12/2020 | Mississippi | at | Texas A&M (9-1,8-1) | PPD | ||||
| 12/19/2020 | Mississippi | 48 | at | LSU (5-5,5-5) | 53 | |||
| 1/2/2021 | Mississippi | 26 | vs | Indiana (6-2) | 20 | Outback Bowl | vs B10 |
| vs Mississippi | vs Other Opponents | Mississippi compared to OOs | |
| Record: | 5-5 | 65-50 | |
| Points Scored: | 38.30 | 28.73 | -9.57 |
| Points Allowed: | 39.20 | 26.83 | 12.37 |
| Margin: | -0.90 | 1.90 | 2.80 |
| Total Points: | 77.50 | 55.56 | 21.94 |