| 8/31/2019 | Georgia (12-2,7-2) | 30 | at | Vanderbilt | 6 | |||
| 9/7/2019 | Vanderbilt | 24 | at | Purdue (4-8) | 42 | at B10 | ||
| 9/21/2019 | LSU (15-0,9-0) | 66 | at | Vanderbilt | 38 | |||
| 9/28/2019 | Northern Illinois (5-7) | 18 | at | Vanderbilt | 24 | MAC | ||
| 10/5/2019 | Vanderbilt | 6 | at | Mississippi (4-8,2-6) | 31 | |||
| 10/12/2019 | UNLV (4-8) | 34 | at | Vanderbilt | 10 | MW | ||
| 10/19/2019 | Missouri (6-6,3-5) | 14 | at | Vanderbilt | 21 | |||
| 11/2/2019 | Vanderbilt | 7 | at | South Carolina (4-8,3-5) | 24 | |||
| 11/9/2019 | Vanderbilt | 0 | at | Florida (11-2,6-2) | 56 | |||
| 11/16/2019 | Kentucky (8-5,3-5) | 38 | at | Vanderbilt | 14 | |||
| 11/23/2019 | East Tennessee St (3-9) | 0 | at | Vanderbilt | 38 | SoCon (1AA) | ||
| 11/30/2019 | Vanderbilt | 10 | at | Tennessee (8-5,5-3) | 28 |
| vs Vanderbilt | vs Other Opponents | Vanderbilt compared to OOs | |
| Record: | 9-3 | 75-65 | |
| Points Scored: | 31.75 | 27.73 | -4.02 |
| Points Allowed: | 16.50 | 23.71 | -7.21 |
| Margin: | 15.25 | 4.02 | -11.23 |
| Total Points: | 48.25 | 51.44 | -3.19 |