| 8/31/2019 | Illinois State (10-5) | 10 | at | Northern Illinois | 24 | MVC (1AA) | ||
| 9/7/2019 | Northern Illinois | 17 | at | Utah (11-3) | 35 | at P12 | ||
| 9/14/2019 | Northern Illinois | 8 | at | Nebraska (5-7) | 44 | at B10 | ||
| 9/28/2019 | Northern Illinois | 18 | at | Vanderbilt (3-9) | 24 | at SEC | ||
| 10/5/2019 | Ball State (5-7,4-4) | 27 | at | Northern Illinois | 20 | |||
| 10/12/2019 | Northern Illinois | 39 | at | Ohio (7-6,5-3) | 36 | |||
| 10/19/2019 | Northern Illinois | 24 | at | Miami-Ohio (8-6,7-2) | 27 | |||
| 10/26/2019 | Akron (0-12,0-8) | 0 | at | Northern Illinois | 49 | |||
| 11/2/2019 | Northern Illinois | 10 | at | Central Michigan (8-6,6-3) | 48 | |||
| 11/13/2019 | Northern Illinois | 31 | at | Toledo (6-6,3-5) | 28 | |||
| 11/19/2019 | Eastern Michigan (6-7,3-5) | 45 | at | Northern Illinois | 17 | |||
| 11/26/2019 | Western Michigan (7-6,5-3) | 14 | at | Northern Illinois | 17 |
| vs Northern Illinois | vs Other Opponents | Northern Illinois compared to OOs | |
| Record: | 7-5 | 69-75 | |
| Points Scored: | 28.17 | 26.63 | -1.54 |
| Points Allowed: | 22.83 | 27.49 | -4.66 |
| Margin: | 5.34 | -0.86 | -6.20 |
| Total Points: | 51.00 | 54.12 | -3.12 |