| 8/31/2019 | North Carolina (7-6) | 24 | vs | South Carolina | 20 | Charlotte NC | ACC | |
| 9/7/2019 | Charleston Southern (6-6) | 10 | at | South Carolina | 72 | BigS (1AA) | ||
| 9/14/2019 | Alabama (11-2,6-2) | 47 | at | South Carolina | 23 | |||
| 9/21/2019 | South Carolina | 14 | at | Missouri (6-6,3-5) | 34 | |||
| 9/28/2019 | Kentucky (8-5,3-5) | 7 | at | South Carolina | 24 | |||
| 10/12/2019 | South Carolina | 20 | at | Georgia (12-2,7-2) | 17 | 2OT | ||
| 10/19/2019 | Florida (11-2,6-2) | 38 | at | South Carolina | 27 | |||
| 10/26/2019 | South Carolina | 21 | at | Tennessee (8-5,5-3) | 41 | |||
| 11/2/2019 | Vanderbilt (3-9,1-7) | 7 | at | South Carolina | 24 | |||
| 11/9/2019 | Appalachian State (13-1) | 20 | at | South Carolina | 15 | SBC | ||
| 11/16/2019 | South Carolina | 6 | at | Texas A&M (8-5,4-4) | 30 | |||
| 11/30/2019 | Clemson (14-1) | 38 | at | South Carolina | 3 | ACC |
| vs South Carolina | vs Other Opponents | South Carolina compared to OOs | |
| Record: | 8-4 | 99-46 | |
| Points Scored: | 26.08 | 31.83 | 5.75 |
| Points Allowed: | 22.42 | 20.36 | 2.06 |
| Margin: | 3.66 | 11.47 | 7.81 |
| Total Points: | 48.50 | 52.19 | -3.69 |