| 8/31/2019 | Mississippi | 10 | at | Memphis (12-2) | 15 | at AAC | ||
| 9/7/2019 | Arkansas (2-10,0-8) | 17 | at | Mississippi | 31 | |||
| 9/14/2019 | Southeastern Louisiana (8-5) | 29 | at | Mississippi | 40 | SLC (1AA) | ||
| 9/21/2019 | California (8-5) | 28 | at | Mississippi | 20 | P12 | ||
| 9/28/2019 | Mississippi | 31 | at | Alabama (11-2,6-2) | 59 | |||
| 10/5/2019 | Vanderbilt (3-9,1-7) | 6 | at | Mississippi | 31 | |||
| 10/12/2019 | Mississippi | 27 | at | Missouri (6-6,3-5) | 38 | |||
| 10/19/2019 | Texas A&M (8-5,4-4) | 24 | at | Mississippi | 17 | |||
| 11/2/2019 | Mississippi | 14 | at | Auburn (9-4,5-3) | 20 | |||
| 11/9/2019 | New Mexico State (2-10) | 3 | at | Mississippi | 41 | Ind | ||
| 11/16/2019 | LSU (15-0,9-0) | 58 | at | Mississippi | 37 | |||
| 11/28/2019 | Mississippi | 20 | at | Mississippi State (6-7,3-5) | 21 |
| vs Mississippi | vs Other Opponents | Mississippi compared to OOs | |
| Record: | 8-4 | 82-61 | |
| Points Scored: | 26.50 | 31.71 | 5.21 |
| Points Allowed: | 26.58 | 26.28 | 0.30 |
| Margin: | -0.08 | 5.43 | 5.51 |
| Total Points: | 53.08 | 57.99 | -4.91 |