| 8/30/2019 | Purdue | 31 | at | Nevada (7-6) | 34 | at MW | ||
| 9/7/2019 | Vanderbilt (3-9) | 24 | at | Purdue | 42 | SEC | ||
| 9/14/2019 | TCU (5-7) | 34 | at | Purdue | 13 | B12 | ||
| 9/28/2019 | Minnesota (11-2,7-2) | 38 | at | Purdue | 31 | |||
| 10/5/2019 | Purdue | 7 | at | Penn State (11-2,7-2) | 35 | |||
| 10/12/2019 | Maryland (3-9,1-8) | 14 | at | Purdue | 40 | |||
| 10/19/2019 | Purdue | 20 | at | Iowa (10-3,6-3) | 26 | |||
| 10/26/2019 | Illinois (6-7,4-5) | 24 | at | Purdue | 6 | |||
| 11/2/2019 | Nebraska (5-7,3-6) | 27 | at | Purdue | 31 | |||
| 11/9/2019 | Purdue | 24 | at | Northwestern (3-9,1-8) | 22 | |||
| 11/23/2019 | Purdue | 24 | at | Wisconsin (10-4,7-3) | 45 | |||
| 11/30/2019 | Indiana (8-5,5-4) | 44 | at | Purdue | 41 | 2OT |
| vs Purdue | vs Other Opponents | Purdue compared to OOs | |
| Record: | 8-4 | 74-66 | |
| Points Scored: | 30.58 | 27.05 | -3.53 |
| Points Allowed: | 25.83 | 24.37 | 1.46 |
| Margin: | 4.75 | 2.68 | -2.07 |
| Total Points: | 56.41 | 51.42 | 4.99 |