| 8/31/2019 | Idaho (5-7) | 7 | at | Penn State | 79 | BSky (1AA) | ||
| 9/7/2019 | Buffalo (8-5) | 13 | at | Penn State | 45 | MAC | ||
| 9/14/2019 | Pittsburgh (8-5) | 10 | at | Penn State | 17 | ACC | ||
| 9/27/2019 | Penn State | 59 | at | Maryland (3-9,1-8) | 0 | |||
| 10/5/2019 | Purdue (4-8,3-6) | 7 | at | Penn State | 35 | |||
| 10/12/2019 | Penn State | 17 | at | Iowa (10-3,6-3) | 12 | |||
| 10/19/2019 | Michigan (9-4,6-3) | 21 | at | Penn State | 28 | |||
| 10/26/2019 | Penn State | 28 | at | Michigan State (7-6,4-5) | 7 | |||
| 11/9/2019 | Penn State | 26 | at | Minnesota (11-2,7-2) | 31 | |||
| 11/16/2019 | Indiana (8-5,5-4) | 27 | at | Penn State | 34 | |||
| 11/23/2019 | Penn State | 17 | at | Ohio State (13-1,10-0) | 28 | |||
| 11/30/2019 | Rutgers (2-10,0-9) | 6 | at | Penn State | 27 | |||
| 12/28/2019 | Memphis (12-2) | 39 | vs | Penn State | 53 | Cotton Bowl - Arlington TX | AAC |
| vs Penn State | vs Other Opponents | Penn State compared to OOs | |
| Record: | 2-11 | 98-56 | |
| Points Scored: | 16.00 | 30.34 | 14.34 |
| Points Allowed: | 35.77 | 23.69 | 12.08 |
| Margin: | -19.77 | 6.65 | 26.42 |
| Total Points: | 51.77 | 54.03 | -2.26 |